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Minor Role of Mitochondrial Respiration for Fatty-Acid Induced Insulin Secretion
An appropriate insulin secretion by pancreatic beta-cells is necessary to maintain glucose homeostasis. A rise in plasma glucose leads to increased metabolism and an elevated cytoplasmic ATP/ADP ratio that finally triggers insulin granule exocytosis. In addition to this triggering pathway, one or mo...
Autores principales: | Schulz, Nadja, Kluth, Oliver, Jastroch, Martin, Schürmann, Annette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794817/ https://www.ncbi.nlm.nih.gov/pubmed/24065099 http://dx.doi.org/10.3390/ijms140918989 |
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