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Emerging targets in cancer management: role of the CXCL12/CXCR4 axis

The chemokine CXCL12 (SDF-1) and its cell surface receptor CXCR4 were first identified as regulators of lymphocyte trafficking to the bone marrow. Soon after, the CXCL12/CXCR4 axis was proposed to regulate the trafficking of breast cancer cells to sites of metastasis. More recently, it was establish...

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Detalles Bibliográficos
Autores principales:	Cojoc, Monica, Peitzsch, Claudia, Trautmann, Franziska, Polishchuk, Leo, Telegeev, Gennady D, Dubrovska, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794844/ https://www.ncbi.nlm.nih.gov/pubmed/24124379 http://dx.doi.org/10.2147/OTT.S36109

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