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Natural Genetic Variation of Integrin Alpha L (Itgal) Modulates Ischemic Brain Injury in Stroke
During ischemic stroke, occlusion of the cerebrovasculature causes neuronal cell death (infarction), but naturally occurring genetic factors modulating infarction have been difficult to identify in human populations. In a surgically induced mouse model of ischemic stroke, we have previously mapped C...
Autores principales: | Keum, Sehoon, Lee, Han Kyu, Chu, Pei-Lun, Kan, Matthew J., Huang, Min-Nung, Gallione, Carol J., Gunn, Michael D., Lo, Donald C., Marchuk, Douglas A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794904/ https://www.ncbi.nlm.nih.gov/pubmed/24130503 http://dx.doi.org/10.1371/journal.pgen.1003807 |
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