Dominant Role of Nucleotide Substitution in the Diversification of Serotype 3 Pneumococci over Decades and during a Single Infection

Streptococcus pneumoniae of serotype 3 possess a mucoid capsule and cause disease associated with high mortality rates relative to other pneumococci. Phylogenetic analysis of a complete reference genome and 81 draft sequences from clonal complex 180, the predominant serotype 3 clone in much of the w...

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Detalles Bibliográficos
Autores principales: Croucher, Nicholas J., Mitchell, Andrea M., Gould, Katherine A., Inverarity, Donald, Barquist, Lars, Feltwell, Theresa, Fookes, Maria C., Harris, Simon R., Dordel, Janina, Salter, Susannah J., Browall, Sarah, Zemlickova, Helena, Parkhill, Julian, Normark, Staffan, Henriques-Normark, Birgitta, Hinds, Jason, Mitchell, Tim J., Bentley, Stephen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794909/
https://www.ncbi.nlm.nih.gov/pubmed/24130509
http://dx.doi.org/10.1371/journal.pgen.1003868

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