Novel Staphylococcal Glycosyltransferases SdgA and SdgB Mediate Immunogenicity and Protection of Virulence-Associated Cell Wall Proteins

Infection of host tissues by Staphylococcus aureus and S. epidermidis requires an unusual family of staphylococcal adhesive proteins that contain long stretches of serine-aspartate dipeptide-repeats (SDR). The prototype member of this family is clumping factor A (ClfA), a key virulence factor that m...

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Detalles Bibliográficos
Autores principales: Hazenbos, Wouter L. W., Kajihara, Kimberly K., Vandlen, Richard, Morisaki, J. Hiroshi, Lehar, Sophie M., Kwakkenbos, Mark J., Beaumont, Tim, Bakker, Arjen Q., Phung, Qui, Swem, Lee R., Ramakrishnan, Satish, Kim, Janice, Xu, Min, Shah, Ishita M., Diep, Binh An, Sai, Tao, Sebrell, Andrew, Khalfin, Yana, Oh, Angela, Koth, Chris, Lin, S. Jack, Lee, Byoung-Chul, Strandh, Magnus, Koefoed, Klaus, Andersen, Peter S., Spits, Hergen, Brown, Eric J., Tan, Man-Wah, Mariathasan, Sanjeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794999/
https://www.ncbi.nlm.nih.gov/pubmed/24130480
http://dx.doi.org/10.1371/journal.ppat.1003653

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