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Human Cytomegalovirus Latency-Associated Proteins Elicit Immune-Suppressive IL-10 Producing CD4(+) T Cells

Human cytomegalovirus (HCMV) is a widely prevalent human herpesvirus, which, after primary infection, persists in the host for life. In healthy individuals, the virus is well controlled by the HCMV-specific T cell response. A key feature of this persistence, in the face of a normally robust host imm...

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Detalles Bibliográficos
Autores principales: Mason, Gavin M., Jackson, Sarah, Okecha, Georgina, Poole, Emma, Sissons, J. G. Patrick, Sinclair, John, Wills, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795018/
https://www.ncbi.nlm.nih.gov/pubmed/24130479
http://dx.doi.org/10.1371/journal.ppat.1003635

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