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Type I Interferon Upregulates Bak and Contributes to T Cell Loss during Human Immunodeficiency Virus (HIV) Infection

The role of Type I interferon (IFN) during pathogenic HIV and SIV infections remains unclear, with conflicting observations suggesting protective versus immunopathological effects. We therefore examined the effect of IFNα/β on T cell death and viremia in HIV infection. Ex vivo analysis of eight pro-...

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Detalles Bibliográficos
Autores principales:	Fraietta, Joseph A., Mueller, Yvonne M., Yang, Guibin, Boesteanu, Alina C., Gracias, Donald T., Do, Duc H., Hope, Jennifer L., Kathuria, Noshin, McGettigan, Shannon E., Lewis, Mark G., Giavedoni, Luis D., Jacobson, Jeffrey M., Katsikis, Peter D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795023/ https://www.ncbi.nlm.nih.gov/pubmed/24130482 http://dx.doi.org/10.1371/journal.ppat.1003658

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