Draft Genome Sequence of a Stable Mucoid Strain of Pseudomonas aeruginosa PAO581 with a mucA25 Mutation

A mutation in the mucA gene, which encodes a negative regulator of alginate production in Pseudomonas aeruginosa, is the main mechanism underlying the conversion to mucoidy in clinical isolates from patients with cystic fibrosis (CF). Here, we announce the draft genome sequence of the stable alginat...

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Detalles Bibliográficos
Autores principales: Yin, Yeshi, Withers, T. Ryan, Govan, John R. W., Johnson, Shannon L., Yu, Hongwei D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2013
Materias:
Prokaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795219/
https://www.ncbi.nlm.nih.gov/pubmed/24115549
http://dx.doi.org/10.1128/genomeA.00834-13
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author Yin, Yeshi
Withers, T. Ryan
Govan, John R. W.
Johnson, Shannon L.
Yu, Hongwei D.
author_facet Yin, Yeshi
Withers, T. Ryan
Govan, John R. W.
Johnson, Shannon L.
Yu, Hongwei D.
author_sort Yin, Yeshi
collection PubMed
description A mutation in the mucA gene, which encodes a negative regulator of alginate production in Pseudomonas aeruginosa, is the main mechanism underlying the conversion to mucoidy in clinical isolates from patients with cystic fibrosis (CF). Here, we announce the draft genome sequence of the stable alginate-overproducing mucoid strain P. aeruginosa PAO581 with a mucA25 mutation, a derivative from the nonmucoid strains P. aeruginosa PAO381 and PAO1.
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spelling pubmed-37952192013-10-11 Draft Genome Sequence of a Stable Mucoid Strain of Pseudomonas aeruginosa PAO581 with a mucA25 Mutation Yin, Yeshi Withers, T. Ryan Govan, John R. W. Johnson, Shannon L. Yu, Hongwei D. Genome Announc Prokaryotes A mutation in the mucA gene, which encodes a negative regulator of alginate production in Pseudomonas aeruginosa, is the main mechanism underlying the conversion to mucoidy in clinical isolates from patients with cystic fibrosis (CF). Here, we announce the draft genome sequence of the stable alginate-overproducing mucoid strain P. aeruginosa PAO581 with a mucA25 mutation, a derivative from the nonmucoid strains P. aeruginosa PAO381 and PAO1. American Society for Microbiology 2013-10-10 /pmc/articles/PMC3795219/ /pubmed/24115549 http://dx.doi.org/10.1128/genomeA.00834-13 Text en Copyright © 2013 Yin et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/) .
spellingShingle Prokaryotes
Yin, Yeshi
Withers, T. Ryan
Govan, John R. W.
Johnson, Shannon L.
Yu, Hongwei D.
Draft Genome Sequence of a Stable Mucoid Strain of Pseudomonas aeruginosa PAO581 with a mucA25 Mutation
title Draft Genome Sequence of a Stable Mucoid Strain of Pseudomonas aeruginosa PAO581 with a mucA25 Mutation
title_full Draft Genome Sequence of a Stable Mucoid Strain of Pseudomonas aeruginosa PAO581 with a mucA25 Mutation
title_fullStr Draft Genome Sequence of a Stable Mucoid Strain of Pseudomonas aeruginosa PAO581 with a mucA25 Mutation
title_full_unstemmed Draft Genome Sequence of a Stable Mucoid Strain of Pseudomonas aeruginosa PAO581 with a mucA25 Mutation
title_short Draft Genome Sequence of a Stable Mucoid Strain of Pseudomonas aeruginosa PAO581 with a mucA25 Mutation
title_sort draft genome sequence of a stable mucoid strain of pseudomonas aeruginosa pao581 with a muca25 mutation
topic Prokaryotes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795219/
https://www.ncbi.nlm.nih.gov/pubmed/24115549
http://dx.doi.org/10.1128/genomeA.00834-13
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