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Induction of Chromosomal Instability via Telomere Dysfunction and Epigenetic Alterations in Myeloid Neoplasia

Chromosomal instability (CIN) is a characteristic feature of cancer. In this review, we concentrate on mechanisms leading to CIN in myeloid neoplasia, i.e., myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML). The pathogenesis of myeloid neoplasia is complex and involves genetic and epige...

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Detalles Bibliográficos
Autores principales:	Vajen, Beate, Thomay, Kathrin, Schlegelberger, Brigitte
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795368/ https://www.ncbi.nlm.nih.gov/pubmed/24202323 http://dx.doi.org/10.3390/cancers5030857

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