PARP-1: Friend or Foe of DNA Damage and Repair in Tumorigenesis?

Oxidative stress induced by reactive oxygen species can result in DNA damage within cells and subsequently increase risk for carcinogenesis. This may be averted by repair of DNA damage through the base or nucleotide excision repair (BER/NER) pathways. PARP, a BER protein, is known for its role in DN...

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Detalles Bibliográficos
Autores principales: Swindall, Amanda F., Stanley, Jennifer A., Yang, Eddy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795373/
https://www.ncbi.nlm.nih.gov/pubmed/24202328
http://dx.doi.org/10.3390/cancers5030943

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