Immune Regulatory Activity of Vitamin D(3) in Head and Neck Cancer

While vitamin D exhibits a multitude of cellular effects that can impact on cancer development and progression, this review focuses on its immune modulatory effects. These immune modulatory effects can be both direct and indirect. Compared to other cancer types, head and neck squamous cell carcinoma...

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Detalles Bibliográficos
Autores principales: Young, M. Rita I., Day, Terry A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795379/
https://www.ncbi.nlm.nih.gov/pubmed/24202334
http://dx.doi.org/10.3390/cancers5031072
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author Young, M. Rita I.
Day, Terry A.
author_facet Young, M. Rita I.
Day, Terry A.
author_sort Young, M. Rita I.
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description While vitamin D exhibits a multitude of cellular effects that can impact on cancer development and progression, this review focuses on its immune modulatory effects. These immune modulatory effects can be both direct and indirect. Compared to other cancer types, head and neck squamous cell carcinomas (HNSCC) have received less attention, but are a fascination immunologically because of the profound extent to which they inhibit immune defenses. This review describes the mechanisms of some of these immune inhibitory processes and how vitamin D can help overcome aspects of this immune suppression.
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spelling pubmed-37953792013-10-21 Immune Regulatory Activity of Vitamin D(3) in Head and Neck Cancer Young, M. Rita I. Day, Terry A. Cancers (Basel) Review While vitamin D exhibits a multitude of cellular effects that can impact on cancer development and progression, this review focuses on its immune modulatory effects. These immune modulatory effects can be both direct and indirect. Compared to other cancer types, head and neck squamous cell carcinomas (HNSCC) have received less attention, but are a fascination immunologically because of the profound extent to which they inhibit immune defenses. This review describes the mechanisms of some of these immune inhibitory processes and how vitamin D can help overcome aspects of this immune suppression. MDPI 2013-08-14 /pmc/articles/PMC3795379/ /pubmed/24202334 http://dx.doi.org/10.3390/cancers5031072 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Young, M. Rita I.
Day, Terry A.
Immune Regulatory Activity of Vitamin D(3) in Head and Neck Cancer
title Immune Regulatory Activity of Vitamin D(3) in Head and Neck Cancer
title_full Immune Regulatory Activity of Vitamin D(3) in Head and Neck Cancer
title_fullStr Immune Regulatory Activity of Vitamin D(3) in Head and Neck Cancer
title_full_unstemmed Immune Regulatory Activity of Vitamin D(3) in Head and Neck Cancer
title_short Immune Regulatory Activity of Vitamin D(3) in Head and Neck Cancer
title_sort immune regulatory activity of vitamin d(3) in head and neck cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795379/
https://www.ncbi.nlm.nih.gov/pubmed/24202334
http://dx.doi.org/10.3390/cancers5031072
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