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Microscopic Colitis and Reproductive Factors Related to Exposure to Estrogens and Progesterone
Microscopic colitis (MC) often debuts around or after menopause and is divided into lymphocytic- and collagenous colitis. The aim of this study was to examine whether factors influencing sex hormone levels differed between subgroups of MC as well as between patients and controls. A self-administered...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795533/ https://www.ncbi.nlm.nih.gov/pubmed/24137050 http://dx.doi.org/10.4137/DTI.S12889 |
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author | Roth, Bodil Manjer, Jonas Ohlsson, Bodil |
author_facet | Roth, Bodil Manjer, Jonas Ohlsson, Bodil |
author_sort | Roth, Bodil |
collection | PubMed |
description | Microscopic colitis (MC) often debuts around or after menopause and is divided into lymphocytic- and collagenous colitis. The aim of this study was to examine whether factors influencing sex hormone levels differed between subgroups of MC as well as between patients and controls. A self-administered questionnaire about parity was completed which included questions surrounding age at first childbirth, menarche and menopause, the use of oral contraceptives, and hormonal replacement therapy. Patients with lymphocytic colitis had children less often compared to those with collagenous colitis (OR = 0.20, 95% CI = 0.05–0.86), however no differences were observed between patients with persistent or transient disease. Patients were less often older than 15 years of age at menarche (OR = 0.48, 95% CI = 0.26–0.91) and were younger at menopause (OR = 0.30, 95% CI = 0.16–0.56) compared with controls. Thus, no obvious association between factors influencing sex hormone levels and presence of MC could be found. |
format | Online Article Text |
id | pubmed-3795533 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Libertas Academica |
record_format | MEDLINE/PubMed |
spelling | pubmed-37955332013-10-17 Microscopic Colitis and Reproductive Factors Related to Exposure to Estrogens and Progesterone Roth, Bodil Manjer, Jonas Ohlsson, Bodil Drug Target Insights Original Research Microscopic colitis (MC) often debuts around or after menopause and is divided into lymphocytic- and collagenous colitis. The aim of this study was to examine whether factors influencing sex hormone levels differed between subgroups of MC as well as between patients and controls. A self-administered questionnaire about parity was completed which included questions surrounding age at first childbirth, menarche and menopause, the use of oral contraceptives, and hormonal replacement therapy. Patients with lymphocytic colitis had children less often compared to those with collagenous colitis (OR = 0.20, 95% CI = 0.05–0.86), however no differences were observed between patients with persistent or transient disease. Patients were less often older than 15 years of age at menarche (OR = 0.48, 95% CI = 0.26–0.91) and were younger at menopause (OR = 0.30, 95% CI = 0.16–0.56) compared with controls. Thus, no obvious association between factors influencing sex hormone levels and presence of MC could be found. Libertas Academica 2013-10-07 /pmc/articles/PMC3795533/ /pubmed/24137050 http://dx.doi.org/10.4137/DTI.S12889 Text en © 2013 the author(s), publisher and licensee Libertas Academica Ltd. This is an open access article published under the Creative Commons CC-BY-NC 3.0 license. |
spellingShingle | Original Research Roth, Bodil Manjer, Jonas Ohlsson, Bodil Microscopic Colitis and Reproductive Factors Related to Exposure to Estrogens and Progesterone |
title | Microscopic Colitis and Reproductive Factors Related to Exposure to Estrogens and Progesterone |
title_full | Microscopic Colitis and Reproductive Factors Related to Exposure to Estrogens and Progesterone |
title_fullStr | Microscopic Colitis and Reproductive Factors Related to Exposure to Estrogens and Progesterone |
title_full_unstemmed | Microscopic Colitis and Reproductive Factors Related to Exposure to Estrogens and Progesterone |
title_short | Microscopic Colitis and Reproductive Factors Related to Exposure to Estrogens and Progesterone |
title_sort | microscopic colitis and reproductive factors related to exposure to estrogens and progesterone |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795533/ https://www.ncbi.nlm.nih.gov/pubmed/24137050 http://dx.doi.org/10.4137/DTI.S12889 |
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