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Creation and structure determination of an artificial protein with three complete sequence repeats

Symfoil-4P is a de novo protein exhibiting the threefold symmetrical β-trefoil fold designed based on the human acidic fibroblast growth factor. First three asparagine–glycine sequences of Symfoil-4P are replaced with glutamine–glycine (Symfoil-QG) or serine–glycine (Symfoil-SG) sequences protecting...

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Detalles Bibliográficos
Autores principales: Adachi, Motoyasu, Shimizu, Rumi, Kuroki, Ryota, Blaber, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795563/
https://www.ncbi.nlm.nih.gov/pubmed/24121347
http://dx.doi.org/10.1107/S0909049513022164

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