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Crystal structure of human CK2α at 1.06 Å resolution

The Ser/Thr kinase CK2 consists of two catalytic subunits (CK2α) and a dimer of the regulatory subunits (CK2β), and is a ubiquitous enzyme that regulates growth, proliferation and the survival of cells. CK2 is a remarkable drug target for potentially treating a wide variety of tumours and glomerulon...

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Detalles Bibliográficos
Autores principales: Kinoshita, Takayoshi, Nakaniwa, Tetsuko, Sekiguchi, Yusuke, Sogabe, Yuri, Sakurai, Atsushi, Nakamura, Shinya, Nakanishi, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795567/
https://www.ncbi.nlm.nih.gov/pubmed/24121351
http://dx.doi.org/10.1107/S0909049513020785