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Crystal structure of human CK2α at 1.06 Å resolution
The Ser/Thr kinase CK2 consists of two catalytic subunits (CK2α) and a dimer of the regulatory subunits (CK2β), and is a ubiquitous enzyme that regulates growth, proliferation and the survival of cells. CK2 is a remarkable drug target for potentially treating a wide variety of tumours and glomerulon...
Autores principales: | Kinoshita, Takayoshi, Nakaniwa, Tetsuko, Sekiguchi, Yusuke, Sogabe, Yuri, Sakurai, Atsushi, Nakamura, Shinya, Nakanishi, Isao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795567/ https://www.ncbi.nlm.nih.gov/pubmed/24121351 http://dx.doi.org/10.1107/S0909049513020785 |
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