Zidovudine (AZT) and Hepatic Lipid Accumulation: Implication of Inflammation, Oxidative and Endoplasmic Reticulum Stress Mediators

The clinical effectiveness of Zidovudine (AZT) is constrained due to its side-effects including hepatic steatosis and toxicity. However, the mechanism(s) of hepatic lipid accumulation in AZT-treated individuals is unknown. We hypothesized that AZT-mediated oxidative and endoplasmic reticulum (ER) st...

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Detalles Bibliográficos
Autores principales: Banerjee, Atrayee, Abdelmegeed, Mohamed A., Jang, Sehwan, Song, Byoung-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795627/
https://www.ncbi.nlm.nih.gov/pubmed/24146933
http://dx.doi.org/10.1371/journal.pone.0076850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795627/
https://www.ncbi.nlm.nih.gov/pubmed/24146933
http://dx.doi.org/10.1371/journal.pone.0076850

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