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Four Amino Acids within a Tandem QxVx Repeat in a Predicted Extended α-Helix of the Smad-Binding Domain of Sip1 Are Necessary for Binding to Activated Smad Proteins
The zinc finger transcription factor Smad-interacting protein-1 (Sip1; Zeb2, Zfhx1b) plays an important role during vertebrate embryogenesis in various tissues and differentiating cell types, and during tumorigenesis. Previous biochemical analysis suggests that interactions with several partner prot...
Autores principales: | Conidi, Andrea, van den Berghe, Veronique, Leslie, Kris, Stryjewska, Agata, Xue, Hua, Chen, Ye-Guang, Seuntjens, Eve, Huylebroeck, Danny |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795639/ https://www.ncbi.nlm.nih.gov/pubmed/24146916 http://dx.doi.org/10.1371/journal.pone.0076733 |
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