Iron Accumulates in Huntington’s Disease Neurons: Protection by Deferoxamine

Huntington’s disease (HD) is a progressive neurodegenerative disorder caused by a polyglutamine-encoding CAG expansion in the huntingtin gene. Iron accumulates in the brains of HD patients and mouse disease models. However, the cellular and subcellular sites of iron accumulation, as well as signific...

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Detalles Bibliográficos
Autores principales: Chen, Jianfang, Marks, Eileen, Lai, Barry, Zhang, Zhaojie, Duce, James A., Lam, Linh Q., Volitakis, Irene, Bush, Ashley I., Hersch, Steven, Fox, Jonathan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795666/
https://www.ncbi.nlm.nih.gov/pubmed/24146952
http://dx.doi.org/10.1371/journal.pone.0077023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795666/
https://www.ncbi.nlm.nih.gov/pubmed/24146952
http://dx.doi.org/10.1371/journal.pone.0077023

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