Cargando…

Genetic Analysis of a Rat Model of Aerobic Capacity and Metabolic Fitness

Aerobic capacity is a strong predictor of all-cause mortality and can influence many complex traits. To explore the biological basis underlying this connection, we developed via artificial selection two rat lines that diverge for intrinsic (i.e. inborn) aerobic capacity and differ in risk for comple...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ren, Yu-yu, Overmyer, Katherine A., Qi, Nathan R., Treutelaar, Mary K., Heckenkamp, Lori, Kalahar, Molly, Koch, Lauren G., Britton, Steven L., Burant, Charles F., Li, Jun Z.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795692/ https://www.ncbi.nlm.nih.gov/pubmed/24147032 http://dx.doi.org/10.1371/journal.pone.0077588

Ejemplares similares

Intrinsic cardiorespiratory fitness modulates clinical and molecular response to caloric restriction
por: Fleischman, Johanna Y., et al.
Publicado: (2023)

Genetic Models of Aerobic Endurance Running Capacity in Rats
por: Britton, Steven L., et al.
Publicado: (2002)

Impact of Anesthesia and Euthanasia on Metabolomics of Mammalian Tissues: Studies in a C57BL/6J Mouse Model
por: Overmyer, Katherine A., et al.
Publicado: (2015)

Brain diabetic neurodegeneration segregates with low intrinsic aerobic capacity
por: Choi, Joungil, et al.
Publicado: (2014)

Low Intrinsic Aerobic Capacity Limits Recovery Response to Hindlimb Ischemia
por: Granier, Elizabeth, et al.
Publicado: (2021)

The Effect of Age and Intrinsic Aerobic Exercise Capacity on the Expression of Inflammation and Remodeling Markers in Rat Achilles Tendons
por: Kinitz, Runa, et al.
Publicado: (2021)

Hydrocephalus Following Experimental Subarachnoid Hemorrhage in Rats with Different Aerobic Capacity
por: Toyota, Yasunori, et al.
Publicado: (2021)

Augmented Cardiac Mitochondrial Capacity in High Capacity Aerobic Running “Disease-Resistant” Phenotype at Rest Is Lost Following Ischemia Reperfusion
por: Alsahly, Musaad B., et al.
Publicado: (2021)

Influence of Intrinsic Aerobic Exercise Capacity and Sex on Cardiac Injury Following Acute Myocardial Ischemia and Reperfusion
por: Alsahly, Musaad B., et al.
Publicado: (2021)

Artificial Selection for Whole Animal Low Intrinsic Aerobic Capacity Co-Segregates with Hypoxia-Induced Cardiac Pump Failure
por: Palpant, Nathan J., et al.
Publicado: (2009)

Ovariectomy results in differential shifts in gut microbiota in low versus high aerobic capacity rats
por: Cox-York, Kimberly A, et al.
Publicado: (2015)

Voluntary Running Aids to Maintain High Body Temperature in Rats Bred for High Aerobic Capacity
por: Karvinen, Sira M., et al.
Publicado: (2016)

Skeletal muscle heme oxygenase-1 activity regulates aerobic capacity
por: de Souza, Rodrigo W. Alves, et al.
Publicado: (2021)

Atrial Myocyte Function and Ca(2+) Handling Is Associated with Inborn Aerobic Capacity
por: Johnsen, Anne Berit, et al.
Publicado: (2013)

Differences in intrinsic aerobic capacity alters sensitivity to ischemia-reperfusion injury but not cardioprotective capacity by ischemic preconditioning in rats
por: Hjortbak, Marie Vognstoft, et al.
Publicado: (2020)

Skeletal muscle metabolism in rats with low and high intrinsic aerobic capacity: Effect of aging and exercise training
por: Shi, Mingshu, et al.
Publicado: (2018)

High Intrinsic Aerobic Capacity Protects against Ethanol-Induced Hepatic Injury and Metabolic Dysfunction: Study Using High Capacity Runner Rat Model
por: Szary, Nicholas, et al.
Publicado: (2015)

Reduced contextually induced muscle thermogenesis in rats with calorie restriction and lower aerobic fitness but not monogenic obesity
por: Shemery, Ashley M., et al.
Publicado: (2023)

Rats Bred for Low Aerobic Capacity Become Promptly Fatigued and Have Slow Metabolic Recovery after Stimulated, Maximal Muscle Contractions
por: Torvinen, Sira, et al.
Publicado: (2012)

The Influence of Childhood Aerobic Fitness on Learning and Memory
por: Raine, Lauren B., et al.
Publicado: (2013)

Comparative Analysis of Skeletal Muscle Transcriptional Signatures Associated With Aerobic Exercise Capacity or Response to Training in Humans and Rats
por: Kelahmetoglu, Yildiz, et al.
Publicado: (2020)

Gene expression centroids that link with low intrinsic aerobic exercise capacity and complex disease risk
por: Kivelä, Riikka, et al.
Publicado: (2010)

Divergent role of nitric oxide in insulin-stimulated aortic vasorelaxation between low- and high-intrinsic aerobic capacity rats
por: Crissey, Jacqueline M, et al.
Publicado: (2015)

Correction: Genetic Analysis of a Rat Model of Aerobic Capacity and Metabolic Fitness
Publicado: (2014)

Denervation and senescence markers data from old rats with intrinsic differences in responsiveness to aerobic training
por: Brown, Lemuel A., et al.
Publicado: (2019)

Interactive effects of aging and aerobic capacity on energy metabolism–related metabolites of serum, skeletal muscle, and white adipose tissue
por: Zhuang, Haihui, et al.
Publicado: (2021)

Life‐long exercise training and inherited aerobic endurance capacity produce converging gut microbiome signatures in rodents
por: Anhê, Fernando F., et al.
Publicado: (2022)

Physical Activity Differentially Affects the Cecal Microbiota of Ovariectomized Female Rats Selectively Bred for High and Low Aerobic Capacity
por: Liu, Tzu-Wen, et al.
Publicado: (2015)

Differential regulation of cysteine oxidative post-translational modifications in high and low aerobic capacity
por: Souza, Rodrigo W. A., et al.
Publicado: (2018)

The relationship of aerobic capacity, anaerobic peak power and experience to performance in CrossFit exercise
por: Bellar, D, et al.
Publicado: (2015)

Effect of aerobic fitness on capillary blood volume and diffusing membrane capacity responses to exercise
por: Tedjasaputra, Vincent, et al.
Publicado: (2016)

Aerobic Fitness Markers Associated with Post-Paddling Breath-hold Capacity in Competitive Surfers
por: GREEVER, CORY J., et al.
Publicado: (2019)

Aerobic Fitness, B-Vitamins, and Weight Status Are Related to Selective Attention in Children
por: Raine, Lauren B., et al.
Publicado: (2021)

Alterations in Lipid Signaling Underlie Lipodystrophy Secondary to AGPAT2 Mutations
por: Subauste, Angela R., et al.
Publicado: (2012)

Higher mitochondrial oxidative capacity is the primary molecular differentiator in muscle of rats with high and low intrinsic cardiorespiratory fitness
por: Fleischman, Johanna Y., et al.
Publicado: (2023)

Label-Free LC-MS Profiling of Skeletal Muscle Reveals Heart-Type Fatty Acid Binding Protein as a Candidate Biomarker of Aerobic Capacity
por: Malik, Zulezwan A., et al.
Publicado: (2013)

Rats Genetically Selected for High Aerobic Exercise Capacity Have Elevated Plasma Bilirubin by Upregulation of Hepatic Biliverdin Reductase-A (BVRA) and Suppression of UGT1A1
por: Hinds, Terry D., et al.
Publicado: (2020)

Conditional independence mapping of DIGE data reveals PDIA3 protein species as key nodes associated with muscle aerobic capacity
por: Burniston, Jatin G., et al.
Publicado: (2014)

Aerobic fitness is associated with greater white matter integrity in children
por: Chaddock-Heyman, Laura, et al.
Publicado: (2014)

Intrinsic Aerobic Capacity Affects Hippocampal pAkt and HSP72 Response to an Acute High Fat Diet and Heat Treatment in Rats
por: Gan, Li, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_5hrjkpbhucqo27ah0gr8n4tf6i