Autocrine Extra-Pancreatic Trypsin 3 Secretion Promotes Cell Proliferation and Survival in Esophageal Adenocarcinoma

Trypsin or Tumor associated trypsin (TAT) activation of Protease-activated receptor 2 (PAR-2) promotes tumor cell proliferation in gastrointestinal cancers. The role of the trypsin/PAR-2 network in esophageal adenocarcinoma (EA) development has not yet been investigated. The aim of this study is to...

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Detalles Bibliográficos
Autores principales: Han, Song, Lee, Constance W., Trevino, Jose G., Hughes, Steven J., Sarosi, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795734/
https://www.ncbi.nlm.nih.gov/pubmed/24146905
http://dx.doi.org/10.1371/journal.pone.0076667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795734/
https://www.ncbi.nlm.nih.gov/pubmed/24146905
http://dx.doi.org/10.1371/journal.pone.0076667

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