Cargando…

Autocrine Extra-Pancreatic Trypsin 3 Secretion Promotes Cell Proliferation and Survival in Esophageal Adenocarcinoma

Trypsin or Tumor associated trypsin (TAT) activation of Protease-activated receptor 2 (PAR-2) promotes tumor cell proliferation in gastrointestinal cancers. The role of the trypsin/PAR-2 network in esophageal adenocarcinoma (EA) development has not yet been investigated. The aim of this study is to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Song, Lee, Constance W., Trevino, Jose G., Hughes, Steven J., Sarosi, George A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795734/ https://www.ncbi.nlm.nih.gov/pubmed/24146905 http://dx.doi.org/10.1371/journal.pone.0076667

Ejemplares similares

SPARC promotes pancreatic cancer cell proliferation and migration through autocrine secretion into the extracellular milieu
por: Pan, Kehua, et al.
Publicado: (2021)

Glutamate secretion by embryonic stem cells as an autocrine signal to promote proliferation
por: Teng, Lin, et al.
Publicado: (2023)

Dictyostelium cells bind a secreted autocrine factor that represses cell proliferation
por: Choe, Jonathan M, et al.
Publicado: (2009)

ATP is an essential autocrine factor for pancreatic β‐cell signaling and insulin secretion
por: Hauke, Sebastian, et al.
Publicado: (2022)

IL-33-Induced Cytokine Secretion and Survival of Mouse Eosinophils Is Promoted by Autocrine GM-CSF
por: Willebrand, Ralf, et al.
Publicado: (2016)

Changing Practice Patterns and Improving Survival for Patients with Pancreatic Ductal Adenocarcinoma
por: Underwood, Patrick W., et al.
Publicado: (2023)

Autocrine Prostaglandin E(2) Signaling Promotes Tumor Cell Survival and Proliferation in Childhood Neuroblastoma
por: Rasmuson, Agnes, et al.
Publicado: (2012)

Anti-Müllerian hormone (AMH) autocrine signaling promotes survival and proliferation of ovarian cancer cells
por: Chauvin, Maëva, et al.
Publicado: (2021)

The inflammatory milieu within the pancreatic cancer microenvironment correlates with clinicopathologic parameters, chemoresistance and survival
por: Delitto, Daniel, et al.
Publicado: (2015)

Significance of serglycin and its binding partners in autocrine promotion of metastasis in esophageal cancer
por: Zhu, Yun, et al.
Publicado: (2021)

Interleukin-4 enhances proliferation of human pancreatic cancer cells: evidence for autocrine and paracrine actions
por: Prokopchuk, O, et al.
Publicado: (2005)

Preclinical testing of dabigatran in trypsin-dependent pancreatitis
por: Pesei, Zsófia Gabriella, et al.
Publicado: (2022)

MCOLN1 Promotes Proliferation and Predicts Poor Survival of Patients with Pancreatic Ductal Adenocarcinoma
por: Hu, Zhan-Dong, et al.
Publicado: (2019)

Pancreatic cancer cells require an EGF receptor-mediated autocrine pathway for proliferation in serum-free conditions
por: Murphy, L O, et al.
Publicado: (2001)

Autocrine signals enable chondrocytes to survive in culture
Publicado: (1994)

Rhizoma Pinelliae trypsin inhibitor separation, purification and inhibitory activity on the proliferation of BGC-823 gastric adenocarcinoma cells
por: ZU, GUOHONG, et al.
Publicado: (2014)

WNT7B mediates autocrine Wnt/β-catenin signaling and anchorage-independent growth in pancreatic adenocarcinoma
por: Arensman, Michael D., et al.
Publicado: (2013)

Osteopenia is associated with wasting in pancreatic adenocarcinoma and predicts survival after surgery
por: Cameron, Miles E., et al.
Publicado: (2021)

Genetic Risk in Chronic Pancreatitis: The Trypsin-Dependent Pathway
por: Hegyi, Eszter, et al.
Publicado: (2017)

Chronic Effects of Palmitate Overload on Nutrient-Induced Insulin Secretion and Autocrine Signalling in Pancreatic MIN6 Beta Cells
por: Watson, Maria L., et al.
Publicado: (2011)

Type IV collagen stimulates pancreatic cancer cell proliferation, migration, and inhibits apoptosis through an autocrine loop
por: Öhlund, Daniel, et al.
Publicado: (2013)

THE INACTIVATION OF TRYPSIN : IV. THE ADSORPTION OF TRYPSIN BY CHARCOAL.
por: Northrop, John H.
Publicado: (1923)

Schwann cell proliferation in vitro is under negative autocrine control
Publicado: (1990)

20-HETE promotes glucose-stimulated insulin secretion in an autocrine manner through FFAR1
por: Tunaru, Sorin, et al.
Publicado: (2018)

Expression of pancreatic secretory trypsin inhibitor (PSTI) in colorectal cancer.
por: Higashiyama, M., et al.
Publicado: (1990)

Framework for Interpretation of Trypsin–antitrypsin Imbalance and Genetic Heterogeneity in Pancreatitis
por: Lin, Kun, et al.
Publicado: (2015)

Trypsin-Mediated Sensitization to Ferroptosis Increases the Severity of Pancreatitis in Mice
por: Liu, Ke, et al.
Publicado: (2021)

Activation of Human Pancreatic Proteolytic Enzymes: The Role of Enteropeptidase and Trypsin
por: Freiburghaus, Andreas U., et al.
Publicado: (2021)

CXCL5 promotes the proliferation and migration of glioma cells in autocrine- and paracrine-dependent manners
por: Dai, Zhijie, et al.
Publicado: (2021)

Autocrine Secretion of Interferon γ Negatively Regulates Homing of Immature B Cells
por: Flaishon, Liat, et al.
Publicado: (2000)

ISOLATION FROM BEEF PANCREAS OF CRYSTALLINE TRYPSINOGEN, TRYPSIN, A TRYPSIN INHIBITOR, AND AN INHIBITOR-TRYPSIN COMPOUND
por: Kunitz, M., et al.
Publicado: (1936)

Fibronectin fragments generated by pancreatic trypsin act as endogenous inhibitors of pancreatic tumor growth
por: Resovi, Andrea, et al.
Publicado: (2023)

Substance P Is a Mechanoresponsive, Autocrine Regulator of Human Tenocyte Proliferation
por: Backman, Ludvig J., et al.
Publicado: (2011)

An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea
por: Yin, Wenguang, et al.
Publicado: (2022)

Trypsin in Cancer
Publicado: (1917)

CRYSTALLINE TRYPSIN : IV. REVERSIBILITY OF THE INACTIVATION AND DENATURATION OF TRYPSIN BY HEAT
por: Northrop, John H.
Publicado: (1932)

THE ESTIMATION OF ACTIVE NATIVE TRYPSIN IN THE PRESENCE OF INACTIVE DENATURED TRYPSIN
por: Anson, M. L., et al.
Publicado: (1933)

THE EQUILIBRIUM BETWEEN ACTIVE NATIVE TRYPSIN AND INACTIVE DENATURED TRYPSIN
por: Anson, M. L., et al.
Publicado: (1934)

Diagnosis of pancreatic adenocarcinoma by polymerase chain reaction from pancreatic secretions.
por: Trümper, L. H., et al.
Publicado: (1994)

TRPM2 promotes the proliferation and invasion of pancreatic ductal adenocarcinoma
por: Lin, Rui, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_42otqo89k5ga6jbaf5gs79nts3