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Overnight Resting of PBMC Changes Functional Signatures of Antigen Specific T- Cell Responses: Impact for Immune Monitoring within Clinical Trials
Polyfunctional CD4 or CD8 T cells are proposed to represent a correlate of immune control for persistent viruses as well as for vaccine mediated protection against infection. A well-suited methodology to study complex functional phenotypes of antiviral T cells is the combined staining of intracellul...
Autores principales: | Kutscher, Sarah, Dembek, Claudia J., Deckert, Simone, Russo, Carolina, Körber, Nina, Bogner, Johannes R., Geisler, Fabian, Umgelter, Andreas, Neuenhahn, Michael, Albrecht, Julia, Cosma, Antonio, Protzer, Ulrike, Bauer, Tanja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795753/ https://www.ncbi.nlm.nih.gov/pubmed/24146841 http://dx.doi.org/10.1371/journal.pone.0076215 |
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