Autophagy regulates endothelial cell processing, maturation and secretion of von Willebrand factor

Endothelial secretion of von Willebrand factor (VWF) from intracellular organelles known as Weibel-Palade bodies (WPBs) is required for platelet adhesion to the injured vessel wall. Here, we demonstrate that WPBs are in some cases found near or within autophagosomes and that endothelial autophagosom...

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Detalles Bibliográficos
Autores principales: Torisu, Takehiro, Torisu, Kumiko, Lee, In Hye, Liu, Jie, Malide, Daniela, Combs, Christian A., Wu, Xufeng S., Rovira, Ilsa I., Fergusson, Maria M., Weigert, Roberto, Connelly, Patricia S., Daniels, Mathew P, Komatsu, Masaaki, Cao, Liu, Finkel, Toren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795899/
https://www.ncbi.nlm.nih.gov/pubmed/24056772
http://dx.doi.org/10.1038/nm.3288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795899/
https://www.ncbi.nlm.nih.gov/pubmed/24056772
http://dx.doi.org/10.1038/nm.3288

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