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IL-21 optimizes T cell and humoral responses in the central nervous system during viral encephalitis

Acute coronavirus encephalomyelitis is controlled by T cells while humoral responses suppress virus persistence. This study defines the contribution of interleukin (IL)-21, a regulator of T and B cell function, to central nervous system (CNS) immunity. IL-21 receptor deficiency did not affect periph...

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Detalles Bibliográficos
Autores principales:	Phares, Timothy W., DiSano, Krista D., Hinton, David R., Hwang, Mihyun, Zajac, Allan J., Stohlman, Stephen A., Bergmann, Cornelia C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796038/ https://www.ncbi.nlm.nih.gov/pubmed/23992866 http://dx.doi.org/10.1016/j.jneuroim.2013.07.019

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