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CARMIL leading edge localization depends on a non-canonical PH domain and dimerization

CARMIL is a ~1370 amino acid cytoskeletal scaffold that plays crucial roles in cell motility and tissue development through interactions with cytoskeletal effectors and regulation of capping protein at the leading edge. However, the mechanism of CARMIL leading edge localization is unknown. Here we s...

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Detalles Bibliográficos
Autores principales:	Zwolak, Adam, Yang, Changsong, Feeser, Elizabeth A., Ostap, E. Michael, Svitkina, Tatyana, Dominguez, Roberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796438/ https://www.ncbi.nlm.nih.gov/pubmed/24071777 http://dx.doi.org/10.1038/ncomms3523

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