Targeted Delivery of an Antigenic Peptide to the Endoplasmic Reticulum: Application for Development of a Peptide Therapy for Ankylosing Spondylitis

The development of suitable methods to deliver peptides specifically to the endoplasmic reticulum (ER) can provide some potential therapeutic applications of such peptides. Ankylosing spondylitis (AS) is strongly associated with the expression of human leukocytic antigen-B27 (HLA-B27). HLA-B27 heavy...

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Detalles Bibliográficos
Autores principales: Yu, Hui-Chun, Lu, Ming-Chi, Li, Chin, Huang, Hsien-Lu, Huang, Kuang-Yung, Liu, Su-Qin, Lai, Ning-Sheng, Huang, Hsien-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796468/
https://www.ncbi.nlm.nih.gov/pubmed/24155957
http://dx.doi.org/10.1371/journal.pone.0077451

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