Complete Nucleotide Sequences of Virulence-Resistance Plasmids Carried by Emerging Multidrug-Resistant Salmonella enterica Serovar Typhimurium Isolated from Cattle in Hokkaido, Japan

In the present study, we have shown that virulence-resistance plasmids from emerging multidrug-resistant isolates of Salmonella enterica serovar Typhimurium were derived from a virulence-associated plasmid, essential for systematic invasiveness of S. Typhimurium in mice (pSLT), through acquisition o...

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Autores principales: Tamamura, Yukino, Tanaka, Kiyoshi, Akiba, Masato, Kanno, Toru, Hatama, Shinichi, Ishihara, Ryoko, Uchida, Ikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796477/
https://www.ncbi.nlm.nih.gov/pubmed/24155970
http://dx.doi.org/10.1371/journal.pone.0077644
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author Tamamura, Yukino
Tanaka, Kiyoshi
Akiba, Masato
Kanno, Toru
Hatama, Shinichi
Ishihara, Ryoko
Uchida, Ikuo
author_facet Tamamura, Yukino
Tanaka, Kiyoshi
Akiba, Masato
Kanno, Toru
Hatama, Shinichi
Ishihara, Ryoko
Uchida, Ikuo
author_sort Tamamura, Yukino
collection PubMed
description In the present study, we have shown that virulence-resistance plasmids from emerging multidrug-resistant isolates of Salmonella enterica serovar Typhimurium were derived from a virulence-associated plasmid, essential for systematic invasiveness of S. Typhimurium in mice (pSLT), through acquisition of a large insert containing a resistance island flanked by IS1294 elements. A bla (CMY-2)-carrying plasmid from a cefotaxime-resistant isolate comprised a segment of Escherichia coli plasmid pAR060302 and the replication region (IncFIB) of a virulence-resistance plasmid. These results provide insights into the evolution of drug resistance in emerging clones of S. Typhimurium.
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spelling pubmed-37964772013-10-23 Complete Nucleotide Sequences of Virulence-Resistance Plasmids Carried by Emerging Multidrug-Resistant Salmonella enterica Serovar Typhimurium Isolated from Cattle in Hokkaido, Japan Tamamura, Yukino Tanaka, Kiyoshi Akiba, Masato Kanno, Toru Hatama, Shinichi Ishihara, Ryoko Uchida, Ikuo PLoS One Research Article In the present study, we have shown that virulence-resistance plasmids from emerging multidrug-resistant isolates of Salmonella enterica serovar Typhimurium were derived from a virulence-associated plasmid, essential for systematic invasiveness of S. Typhimurium in mice (pSLT), through acquisition of a large insert containing a resistance island flanked by IS1294 elements. A bla (CMY-2)-carrying plasmid from a cefotaxime-resistant isolate comprised a segment of Escherichia coli plasmid pAR060302 and the replication region (IncFIB) of a virulence-resistance plasmid. These results provide insights into the evolution of drug resistance in emerging clones of S. Typhimurium. Public Library of Science 2013-10-14 /pmc/articles/PMC3796477/ /pubmed/24155970 http://dx.doi.org/10.1371/journal.pone.0077644 Text en © 2013 Tamamura et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Tamamura, Yukino
Tanaka, Kiyoshi
Akiba, Masato
Kanno, Toru
Hatama, Shinichi
Ishihara, Ryoko
Uchida, Ikuo
Complete Nucleotide Sequences of Virulence-Resistance Plasmids Carried by Emerging Multidrug-Resistant Salmonella enterica Serovar Typhimurium Isolated from Cattle in Hokkaido, Japan
title Complete Nucleotide Sequences of Virulence-Resistance Plasmids Carried by Emerging Multidrug-Resistant Salmonella enterica Serovar Typhimurium Isolated from Cattle in Hokkaido, Japan
title_full Complete Nucleotide Sequences of Virulence-Resistance Plasmids Carried by Emerging Multidrug-Resistant Salmonella enterica Serovar Typhimurium Isolated from Cattle in Hokkaido, Japan
title_fullStr Complete Nucleotide Sequences of Virulence-Resistance Plasmids Carried by Emerging Multidrug-Resistant Salmonella enterica Serovar Typhimurium Isolated from Cattle in Hokkaido, Japan
title_full_unstemmed Complete Nucleotide Sequences of Virulence-Resistance Plasmids Carried by Emerging Multidrug-Resistant Salmonella enterica Serovar Typhimurium Isolated from Cattle in Hokkaido, Japan
title_short Complete Nucleotide Sequences of Virulence-Resistance Plasmids Carried by Emerging Multidrug-Resistant Salmonella enterica Serovar Typhimurium Isolated from Cattle in Hokkaido, Japan
title_sort complete nucleotide sequences of virulence-resistance plasmids carried by emerging multidrug-resistant salmonella enterica serovar typhimurium isolated from cattle in hokkaido, japan
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796477/
https://www.ncbi.nlm.nih.gov/pubmed/24155970
http://dx.doi.org/10.1371/journal.pone.0077644
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