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Altered Cardiac Electrophysiology and SUDEP in a Model of Dravet Syndrome

OBJECTIVE: Dravet syndrome is a severe form of intractable pediatric epilepsy with a high incidence of SUDEP: Sudden Unexpected Death in epilepsy. Cardiac arrhythmias are a proposed cause for some cases of SUDEP, yet the susceptibility and potential mechanism of arrhythmogenesis in Dravet syndrome r...

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Detalles Bibliográficos
Autores principales: Auerbach, David S., Jones, Julie, Clawson, Brittany C., Offord, James, Lenk, Guy M., Ogiwara, Ikuo, Yamakawa, Kazuhiro, Meisler, Miriam H., Parent, Jack M., Isom, Lori L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796479/
https://www.ncbi.nlm.nih.gov/pubmed/24155976
http://dx.doi.org/10.1371/journal.pone.0077843

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