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The Impact of KLF2 Modulation on the Transcriptional Program and Function of CD8 T Cells

Krüppel-like factor 2 (KLF2) is a transcription factor that is highly expressed in quiescent T lymphocytes and downregulated in effector T cells. We now show that antigen receptor engagement downregulates KLF2 expression in a graded response determined by the affinity of T cell antigen receptor (TCR...

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Detalles Bibliográficos
Autores principales:	Preston, Gavin C., Feijoo-Carnero, Carmen, Schurch, Nick, Cowling, Victoria H., Cantrell, Doreen A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796494/ https://www.ncbi.nlm.nih.gov/pubmed/24155966 http://dx.doi.org/10.1371/journal.pone.0077537

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