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Intron Retention in the Alternatively Spliced Region of RON Results from Weak 3’ Splice Site Recognition

The RON gene encodes a tyrosine kinase receptor for macrophage-stimulating protein. A constitutively active isoform that arises by skipping of exon 11 is expressed in carcinomas and contributes to an invasive phenotype. However, a high proportion of the mRNA expressed from the endogenous gene, or fr...

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Detalles Bibliográficos
Autores principales:	Smith, Lindsay D., Lucas, Christian M., Eperon, Ian C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796505/ https://www.ncbi.nlm.nih.gov/pubmed/24155930 http://dx.doi.org/10.1371/journal.pone.0077208

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