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Using Bosentan to Treat Paraquat Poisoning-Induced Acute Lung Injury in Rats

BACKGROUND: Paraquat poisoning is well known for causing multiple organ function failure (MODS) and high mortality. Acute lung injury and advanced pulmonary fibrosis are the most serious complications. Bosentan is a dual endothelin receptor antagonist. It plays an important role in treating PF. Ther...

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Detalles Bibliográficos
Autores principales: Zhang, Zhongchen, Jian, Xiangdong, Zhang, Wei, Wang, Jieru, Zhou, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796527/
https://www.ncbi.nlm.nih.gov/pubmed/24155875
http://dx.doi.org/10.1371/journal.pone.0075943