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Phosphorylation of FOXP3 by LCK Downregulates MMP9 Expression and Represses Cell Invasion
Forkhead Box P3 (FOXP3) is a member of the forkhead/winged helix family of the transcription factors and plays an important role not only as a master gene in T-regulatory cells, but also as a tumor suppressor. In this study, we identified lymphocyte-specific protein tyrosine kinase (LCK), which corr...
Autores principales: | Nakahira, Kumiko, Morita, Akihiro, Kim, Nam-Soon, Yanagihara, Itaru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796550/ https://www.ncbi.nlm.nih.gov/pubmed/24155921 http://dx.doi.org/10.1371/journal.pone.0077099 |
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