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Vaccine-Induced Boosting of Influenza Virus-Specific CD4 T Cells in Younger and Aged Humans
Current yearly influenza virus vaccines induce strain-specific neutralizing antibody (NAb) responses providing protective immunity to closely matched viruses. However, these vaccines are often poorly effective in high-risk groups such as the elderly and challenges exist in predicting yearly or emerg...
Autores principales: | Dolfi, Douglas V., Mansfield, Kathleen D., Kurupati, Raj K., Kannan, Senthil, Doyle, Susan A., Ertl, Hildegund C. J., Schmader, Kenneth E., Wherry, E. John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796569/ https://www.ncbi.nlm.nih.gov/pubmed/24155927 http://dx.doi.org/10.1371/journal.pone.0077164 |
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