Proteome wide reduction in AGE modification in streptozotocin induced diabetic mice by hydralazine mediated transglycation

The non-enzymatic reaction between glucose and protein can be chemically reversed by transglycation. Here we report the transglycation activity of hydralazine using a newly developed MALDI-TOF-MS based assay. Hydralazine mediated transglycation of HbA1c, plasma proteins and kidney proteins was demon...

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Detalles Bibliográficos
Autores principales: Kesavan, Suresh K., Bhat, Shweta, Golegaonkar, Sandeep B., Jagadeeshaprasad, Mashanipalya G., Deshmukh, Arati B., Patil, Harshal S., Bhosale, Santosh D., Shaikh, Mahemud L., Thulasiram, Hirekodathakallu V., Boppana, Ramanamurthy, Kulkarni, Mahesh J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796742/
https://www.ncbi.nlm.nih.gov/pubmed/24126953
http://dx.doi.org/10.1038/srep02941

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