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AutoAssemblyD: a graphical user interface system for several genome assemblers

Next-generation sequencing technologies have increased the amount of biological data generated. Thus, bioinformatics has become important because new methods and algorithms are necessary to manipulate and process such data. However, certain challenges have emerged, such as genome assembly using shor...

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Detalles Bibliográficos
Autores principales: Veras, Adonney Allan de Oliveira, de Sá, Pablo Henrique Caracciolo Gomes, Azevedo, Vasco, Silva, Artur, Ramos, Rommel Thiago Jucá
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796888/
https://www.ncbi.nlm.nih.gov/pubmed/24143057
http://dx.doi.org/10.6026/97320630009840
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author Veras, Adonney Allan de Oliveira
de Sá, Pablo Henrique Caracciolo Gomes
Azevedo, Vasco
Silva, Artur
Ramos, Rommel Thiago Jucá
author_facet Veras, Adonney Allan de Oliveira
de Sá, Pablo Henrique Caracciolo Gomes
Azevedo, Vasco
Silva, Artur
Ramos, Rommel Thiago Jucá
author_sort Veras, Adonney Allan de Oliveira
collection PubMed
description Next-generation sequencing technologies have increased the amount of biological data generated. Thus, bioinformatics has become important because new methods and algorithms are necessary to manipulate and process such data. However, certain challenges have emerged, such as genome assembly using short reads and high-throughput platforms. In this context, several algorithms have been developed, such as Velvet, Abyss, Euler-SR, Mira, Edna, Maq, SHRiMP, Newbler, ALLPATHS, Bowtie and BWA. However, most such assemblers do not have a graphical interface, which makes their use difficult for users without computing experience given the complexity of the assembler syntax. Thus, to make the operation of such assemblers accessible to users without a computing background, we developed AutoAssemblyD, which is a graphical tool for genome assembly submission and remote management by multiple assemblers through XML templates. AVAILABILITY: AssemblyD is freely available at https://sourceforge.net/projects/autoassemblyd. It requires Sun jdk 6 or higher.
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spelling pubmed-37968882013-10-18 AutoAssemblyD: a graphical user interface system for several genome assemblers Veras, Adonney Allan de Oliveira de Sá, Pablo Henrique Caracciolo Gomes Azevedo, Vasco Silva, Artur Ramos, Rommel Thiago Jucá Bioinformation Software Next-generation sequencing technologies have increased the amount of biological data generated. Thus, bioinformatics has become important because new methods and algorithms are necessary to manipulate and process such data. However, certain challenges have emerged, such as genome assembly using short reads and high-throughput platforms. In this context, several algorithms have been developed, such as Velvet, Abyss, Euler-SR, Mira, Edna, Maq, SHRiMP, Newbler, ALLPATHS, Bowtie and BWA. However, most such assemblers do not have a graphical interface, which makes their use difficult for users without computing experience given the complexity of the assembler syntax. Thus, to make the operation of such assemblers accessible to users without a computing background, we developed AutoAssemblyD, which is a graphical tool for genome assembly submission and remote management by multiple assemblers through XML templates. AVAILABILITY: AssemblyD is freely available at https://sourceforge.net/projects/autoassemblyd. It requires Sun jdk 6 or higher. Biomedical Informatics 2013-09-23 /pmc/articles/PMC3796888/ /pubmed/24143057 http://dx.doi.org/10.6026/97320630009840 Text en © 2013 Biomedical Informatics This is an open-access article, which permits unrestricted use, distribution, and reproduction in any medium, for non-commercial purposes, provided the original author and source are credited.
spellingShingle Software
Veras, Adonney Allan de Oliveira
de Sá, Pablo Henrique Caracciolo Gomes
Azevedo, Vasco
Silva, Artur
Ramos, Rommel Thiago Jucá
AutoAssemblyD: a graphical user interface system for several genome assemblers
title AutoAssemblyD: a graphical user interface system for several genome assemblers
title_full AutoAssemblyD: a graphical user interface system for several genome assemblers
title_fullStr AutoAssemblyD: a graphical user interface system for several genome assemblers
title_full_unstemmed AutoAssemblyD: a graphical user interface system for several genome assemblers
title_short AutoAssemblyD: a graphical user interface system for several genome assemblers
title_sort autoassemblyd: a graphical user interface system for several genome assemblers
topic Software
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796888/
https://www.ncbi.nlm.nih.gov/pubmed/24143057
http://dx.doi.org/10.6026/97320630009840
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