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Structural and Mechanistic Insight into DNA Unwinding by Deinococcus radiodurans UvrD
DNA helicases are responsible for unwinding the duplex DNA, a key step in many biological processes. UvrD is a DNA helicase involved in several DNA repair pathways. We report here crystal structures of Deinococcus radiodurans UvrD (drUvrD) in complex with DNA in different nucleotide-free and bound s...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797037/ https://www.ncbi.nlm.nih.gov/pubmed/24143224 http://dx.doi.org/10.1371/journal.pone.0077364 |