Generation of Monoclonal Antibody MS17-57 Targeting Secreted Alkaline Phosphatase Ectopically Expressed on the Surface of Gastrointestinal Cancer Cells

BACKGROUND: Therapeutic antibody development is one of the fastest growing areas of the pharmaceutical industry. Generating high-quality monoclonal antibodies against a given therapeutic target is crucial for successful drug development. However, due to immune tolerance, making it difficult to gener...

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Detalles Bibliográficos
Autores principales: Li, Ming, Gao, Jianpeng, Feng, Runhua, Wang, Yuling, Chen, Xuehua, Sun, Jianyu, Zhang, Dongqing, Zhu, Zhenggang, Ellis, Lee M., Lu, Mason, Lee, Jeffrey E., Feng, Zhenqing, Liu, Bingya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797039/
https://www.ncbi.nlm.nih.gov/pubmed/24143229
http://dx.doi.org/10.1371/journal.pone.0077398

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