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OTUD5 Regulates p53 Stability by Deubiquitinating p53

BACKGROUND: The p53 tumour suppressor protein is a transcription factor that prevents oncogenic progression by activating the expression of apoptosis and cell-cycle arrest genes in stressed cells. The stability of p53 is tightly regulated by ubiquitin-dependent degradation, driven mainly by its nega...

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Detalles Bibliográficos
Autores principales:	Luo, Judong, Lu, Zhonghua, Lu, Xujing, Chen, Ling, Cao, Jianping, Zhang, Shuyu, Ling, Yang, Zhou, Xifa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797110/ https://www.ncbi.nlm.nih.gov/pubmed/24143256 http://dx.doi.org/10.1371/journal.pone.0077682

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