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SLCO1B1 and SLC19A1 Gene Variants and Irinotecan-Induced Rapid Response and Survival: A Prospective Multicenter Pharmacogenetics Study of Metastatic Colorectal Cancer

BACKGROUND: Rapid response to chemotherapy in metastatic colorectal cancer (mCRC) patients (response within 12 weeks of chemotherapy) may increase the chance of complete resection and improved survival. Few molecular markers predict irinotecan-induced rapid response and survival. Single-nucleotide p...

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Detalles Bibliográficos
Autores principales: Huang, Liu, Zhang, Tao, Xie, Conghua, Liao, Xin, Yu, Qianqian, Feng, Jueping, Ma, Hong, Dai, Jing, Li, Min, Chen, Jigui, Zang, Aihua, Wang, Qian, Ge, Shuwang, Qin, Kai, Cai, Juan, Yuan, Xianglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797132/
https://www.ncbi.nlm.nih.gov/pubmed/24143213
http://dx.doi.org/10.1371/journal.pone.0077223

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