Effects of intraventricular methotrexate administration on Cuprizone-induced demyelination in mice

We previously showed that intrathecal administration of methotrexate slowed disability progression in multiple sclerosis (MS) patients with progressive disease. In general MS patients with progressive disease respond poorly to anti-inflammatory therapies. In order to better understand the mechanism...

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Detalles Bibliográficos
Autores principales: Mueller, Andre M., Nassery, Adam, Conlon, Hana, Liu, Xinhe, Jun, Esther, Yoon, Bo Hyung, Cristofanilli, Massimiliano, Sadiq, Saud A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797440/
https://www.ncbi.nlm.nih.gov/pubmed/24137109
http://dx.doi.org/10.3389/fnmol.2013.00034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797440/
https://www.ncbi.nlm.nih.gov/pubmed/24137109
http://dx.doi.org/10.3389/fnmol.2013.00034

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