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Optimization of routine KRAS mutation PCR-based testing procedure for rational individualized first-line-targeted therapy selection in metastatic colorectal cancer

KRAS mutation detection represents a crucial issue in metastatic colorectal cancer (mCRC). The optimization of KRAS mutation detection delay enabling rational prescription of first-line treatment in mCRC including anti-EGFR-targeted therapy requires robust and rapid molecular biology techniques. Rou...

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Detalles Bibliográficos
Autores principales:	Chretien, Anne-Sophie, Harlé, Alexandre, Meyer-Lefebvre, Magali, Rouyer, Marie, Husson, Marie, Ramacci, Carole, Harter, Valentin, Genin, Pascal, Leroux, Agnès, Merlin, Jean-Louis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2013
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797557/ https://www.ncbi.nlm.nih.gov/pubmed/24133623 http://dx.doi.org/10.1002/cam4.47

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