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Metformin use and improved response to therapy in rectal cancer
Locally advanced rectal cancer is commonly treated with chemoradiation prior to total mesorectal excision (TME). Studies suggest that metformin may be an effective chemopreventive agent in this disease as well as a possible adjunct to current therapy. In this study, we examined the effect of metform...
Autores principales: | Skinner, Heath D., Crane, Christopher H., Garrett, Christopher R., Eng, Cathy, Chang, George J., Skibber, John M., Rodriguez-Bigas, Miguel A., Kelly, Patrick, Sandulache, Vlad C., Delclos, Marc E., Krishnan, Sunil, Das, Prajnan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797563/ https://www.ncbi.nlm.nih.gov/pubmed/24133632 http://dx.doi.org/10.1002/cam4.54 |
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