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Overexpression of DRAM enhances p53-dependent apoptosis

Tumor suppressor p53-dependent apoptosis is thought to be one of the most important tumor-suppressive mechanisms in human tumorigenesis. Till date, “super p53” mutants exhibiting more potent ability to induce apoptosis than wild-type p53 have been reported. These super p53s may provide a clue for de...

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Detalles Bibliográficos
Autores principales: Takahashi, Masahiro, Kakudo, Yuichi, Takahashi, Shin, Sakamoto, Yasuhiro, Kato, Shunsuke, Ishioka, Chikashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797565/
https://www.ncbi.nlm.nih.gov/pubmed/24133622
http://dx.doi.org/10.1002/cam4.39

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