Cargando…
Current and future G protein-coupled receptor signaling targets for heart failure therapy
Although there have been significant advances in the therapy of heart failure in recent decades, such as the introduction of β-blockers and antagonists of the renin–angiotensin–aldosterone system, this devastating disease still carries tremendous morbidity and mortality in the western world. G prote...
Autores principales: | Siryk-Bathgate, Ashley, Dabul, Samalia, Lymperopoulos, Anastasios |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797606/ https://www.ncbi.nlm.nih.gov/pubmed/24143078 http://dx.doi.org/10.2147/DDDT.S35905 |
Ejemplares similares
-
Suppression of adrenal βarrestin1-dependent aldosterone production by ARBs: head-to-head comparison
por: Dabul, Samalia, et al.
Publicado: (2015) -
βArrestins in Cardiac G Protein-Coupled Receptor Signaling and Function: Partners in Crime or “Good Cop, Bad Cop”?
por: Lymperopoulos, Anastasios, et al.
Publicado: (2013) -
Novel Insights into the Crosstalk between Mineralocorticoid Receptor and G Protein-Coupled Receptors in Heart Adverse Remodeling and Disease
por: Parker, Barbara M., et al.
Publicado: (2018) -
Angiotensin receptor blocker drugs and inhibition of adrenal beta-arrestin-1-dependent aldosterone production: Implications for heart failure therapy
por: Lymperopoulos, Anastasios, et al.
Publicado: (2017) -
GRK2 blockade with βARKct is essential for cardiac β(2)-adrenergic receptor signaling towards increased contractility
por: Salazar, Norma C, et al.
Publicado: (2013)