Trypanosoma brucei cathepsin-L increases arrhythmogenic sarcoplasmic reticulum-mediated calcium release in rat cardiomyocytes

AIMS: African trypanosomiasis, caused by Trypanosoma brucei species, leads to both neurological and cardiac dysfunction and can be fatal if untreated. While the neurological-related pathogenesis is well studied, the cardiac pathogenesis remains unknown. The current study exposed isolated ventricular...

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Detalles Bibliográficos
Autores principales: Elliott, Elspeth B., McCarroll, Douglas, Hasumi, Hisashi, Welsh, Claire E., Panissidi, Amanda A., Jones, Nathaniel G., Rossor, Charlotte L., Tait, Andy, Smith, Godfrey L., Mottram, Jeremy C., Morrison, Liam J., Loughrey, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797627/
https://www.ncbi.nlm.nih.gov/pubmed/23892734
http://dx.doi.org/10.1093/cvr/cvt187

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