Complex Patterns of Chromosome 11 Aberrations in Myeloid Malignancies Target CBL, MLL, DDB1 and LMO2

Exome sequencing of primary tumors identifies complex somatic mutation patterns. Assignment of relevance of individual somatic mutations is difficult and poses the next challenge for interpretation of next generation sequencing data. Here we present an approach how exome sequencing in combination wi...

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Detalles Bibliográficos
Autores principales: Klampfl, Thorsten, Milosevic, Jelena D., Puda, Ana, Schönegger, Andreas, Bagienski, Klaudia, Berg, Tiina, Harutyunyan, Ashot S., Gisslinger, Bettina, Rumi, Elisa, Malcovati, Luca, Pietra, Daniela, Elena, Chiara, Della Porta, Matteo Giovanni, Pieri, Lisa, Guglielmelli, Paola, Bock, Christoph, Doubek, Michael, Dvorakova, Dana, Suvajdzic, Nada, Tomin, Dragica, Tosic, Natasa, Racil, Zdenek, Steurer, Michael, Pavlovic, Sonja, Vannucchi, Alessandro M., Cazzola, Mario, Gisslinger, Heinz, Kralovics, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797696/
https://www.ncbi.nlm.nih.gov/pubmed/24147083
http://dx.doi.org/10.1371/journal.pone.0077819

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