Massively Parallel Sequencing Reveals an Accumulation of De Novo Mutations and an Activating Mutation of LPAR1 in a Patient with Metastatic Neuroblastoma

Neuroblastoma is one of the most genomically heterogeneous childhood malignances studied to date, and the molecular events that occur during the course of the disease are not fully understood. Genomic studies in neuroblastoma have showed only a few recurrent mutations and a low somatic mutation burd...

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Detalles Bibliográficos
Autores principales: Wei, Jun S., Johansson, Peter, Chen, Li, Song, Young K., Tolman, Catherine, Li, Samuel, Hurd, Laura, Patidar, Rajesh, Wen, Xinyu, Badgett, Thomas C., Cheuk, Adam T. C., Marshall, Jean-Claude, Steeg, Patricia S., Vaqué Díez, José P., Yu, Yanlin, Gutkind, J. Silvio, Khan, Javed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797724/
https://www.ncbi.nlm.nih.gov/pubmed/24147068
http://dx.doi.org/10.1371/journal.pone.0077731

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