Stabilizing Exposure of Conserved Epitopes by Structure Guided Insertion of Disulfide Bond in HIV-1 Envelope Glycoprotein

Entry of HIV-1 into target cells requires binding of the viral envelope glycoprotein (Env) to cellular receptors and subsequent conformational changes that culminates in fusion of viral and target cell membranes. Recent structural information has revealed that these conformational transitions are re...

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Detalles Bibliográficos
Autores principales: Kassa, Aemro, Dey, Antu K., Sarkar, Pampi, Labranche, Celia, Go, Eden P., Clark, Daniel F., Sun, Yide, Nandi, Avishek, Hartog, Karin, Desaire, Heather, Montefiori, David, Carfi, Andrea, Srivastava, Indresh K., Barnett, Susan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797752/
https://www.ncbi.nlm.nih.gov/pubmed/24146829
http://dx.doi.org/10.1371/journal.pone.0076139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797752/
https://www.ncbi.nlm.nih.gov/pubmed/24146829
http://dx.doi.org/10.1371/journal.pone.0076139

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