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Confidence-Guided Local Structure Prediction with HHfrag

We present a method to assess the reliability of local structure prediction from sequence. We introduce a greedy algorithm for filtering and enrichment of dynamic fragment libraries, compiled with remote-homology detection methods such as HHfrag. After filtering false hits at each target position, w...

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Detalles Bibliográficos
Autores principales: Kalev, Ivan, Habeck, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797814/
https://www.ncbi.nlm.nih.gov/pubmed/24146881
http://dx.doi.org/10.1371/journal.pone.0076512