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Direct Induction of Chondrogenic Cells from Human Dermal Fibroblast Culture by Defined Factors
The repair of large cartilage defects with hyaline cartilage continues to be a challenging clinical issue. We recently reported that the forced expression of two reprogramming factors (c-Myc and Klf4) and one chondrogenic factor (SOX9) can induce chondrogenic cells from mouse dermal fibroblast cultu...
Autores principales: | Outani, Hidetatsu, Okada, Minoru, Yamashita, Akihiro, Nakagawa, Kanako, Yoshikawa, Hideki, Tsumaki, Noriyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797820/ https://www.ncbi.nlm.nih.gov/pubmed/24146984 http://dx.doi.org/10.1371/journal.pone.0077365 |
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